Ankylosing spondylitis

Ankylosing spondylitis

- Ankylosing spondylitis or AS, is a form of arthritis that primarily affects the spine, although other joints can become involved.
- It causes inflammation of the spinal joints (vertebrae) that can lead to severe, chronic pain and discomfort.
- Most people with AS have an antigen called HLA-B27
- Ankylosing spondylitis (AS) is a chronic, multisystem inflammatory disorder involving primarily the sacroiliac joints and the axial skeleton.

Key components of the patient history that suggest AS include the following:

• Insidious onset of low back pain - The most common symptom
• Onset of symptoms before age 40 years
• Presence of symptoms for more than 3 months
• Symptoms worse in the morning or with inactivity
• Improvement of symptoms with exercise

Complications

- AS can cause pain and inflammation in other parts of your body.
- Eyes. About 40% of people with AS have an eye problem called uveitis. It’s a painful inflammation that can blur your vision and make you sensitive to bright light.
- Heart valve. It’s not common, but AS can enlarge the aorta, the largest artery in your body. This can change the shape of the aortic valve, which can allow blood to leak back into your heart.
- Cancer. A large study found that people with AS are more likely to get certain types of cancers. They include bone and prostate cancers in men and colon cancer in women, as well as blood-related cancers in both sexes.

Related Questions SPINE

- Ankylosing spondylitis or AS, is a form of arthritis that primarily affects the spine, although other joints can become involved.
- It causes inflammation of the spinal joints (vertebrae) that can lead to severe, chronic pain and discomfort.
- Most people with AS have an antigen called HLA-B27
- Ankylosing spondylitis (AS) is a chronic, multisystem inflammatory disorder involving primarily the sacroiliac joints and the axial skeleton.

Key components of the patient history that suggest AS include the following:

• Insidious onset of low back pain - The most common symptom
• Onset of symptoms before age 40 years
• Presence of symptoms for more than 3 months
• Symptoms worse in the morning or with inactivity
• Improvement of symptoms with exercise

Complications

- AS can cause pain and inflammation in other parts of your body.
- Eyes. About 40% of people with AS have an eye problem called uveitis. It’s a painful inflammation that can blur your vision and make you sensitive to bright light.
- Heart valve. It’s not common, but AS can enlarge the aorta, the largest artery in your body. This can change the shape of the aortic valve, which can allow blood to leak back into your heart.
- Cancer. A large study found that people with AS are more likely to get certain types of cancers. They include bone and prostate cancers in men and colon cancer in women, as well as blood-related cancers in both sexes.